Radiotherapy Treatment for Melanoma Skin Cancer Disease
Abstract
Background: Melanoma is a skin disorder caused by malignant degeneration of the pigment cells melanocytes. The disease is characterized by widespread discoloration with irregular and protruding edges. In treating cancer itself, radiotherapy technology, has been found. It is a method of treating cancer using high-energy radiation rays that are focused on cancerous tissue to kill or stop cancer cell division. This study aims to determine the effectiveness of radiotherapy technology as a treatment solution for melanoma skin cancer. The focuses of the study in this paper are the integumentary system and skin structure, melanoma skin cancer, the body's mechanisms for melanoma skin cancer, and radiotherapy as a treatment method. Methods: The research method used is literature study from various sources, to help understand the problem more deeply and completely. Conclusions: Melanoma, which attacks one of the body's integumentary systems, namely the skin, has a close relationship with homeostatic dysregulation and endocrine damage. However, radiotherapy method can be used to cure melanoma skin cancer by shooting X-rays and damaging the cancer cells and also reducing their spread to other parts of the organs. This method is effective because melanoma skin cancer is localized or has not spread to other organs. However, the use of radiotherapy can also have a negative impact on the body and can give unwanted side effects, so consideration is needed before using this method.
Full text article
References
Ardhiansia, A. O. (2019). Surgery mapping seri onkologi: kanker kulit dan sarkoma jaringan lunak. Surabaya: Airlangga University Press.
Baskar, R., Lee, K. A., Yeo, R., & Yeoh, K. W. (2012). Cancer and radiation therapy: Current advances and future directions. International Journal of Medical Sciences, 9(3), 193-199.
Bolon, C. M., Siregar , D., Kartika , L., Supinganto, A., Manurung, S. S., Sitanggang, Y. F., & Noradina. (2020). Anatomi dan fisiologi untuk mahasiswa kebidanan. Medan: Yayasan Kita Menulis.
Brown, R. G., & Burns, T. (2005). Dermatologi. Jakarta: Airlangga.
Campbell, Reece, & Mitchell. (2002). Biologi Jilid 1, Edisi 5. Jakarta: Erlangga.
Cancerhelps. (2014). Bebas kanker itu mudah. Jakarta: FMedia.
Ferrari, R. (2015). Writing narrative style literature reviews. The European Medical Writers Association, 24(4), 230-235.
Fitriatuzzakiyyah, N., Sinuraya, R. K., & Puspitasari, I. M. (2017). Terapi kanker dengan radiasi: Konsep dasar radioterapi dan perkembangannya di Indonesia. Jurnal Farmasi Klinik Indonesia, 6(4), 311-320.
Garau, M. M., Calduch, A. L., & Lopez, E. C. 2011. Review: Radiobiology of the acute radiation syndrome. Reports of Practical Oncology and Radiotherapy, 123-130.
Hanum, F. J., & Supriana, N. (2019). Peran radioterapi pada melanoma kulit. Jurnal of the Indonesian radiation oncology society, 10, 22-26.
Hendaria, M., Asmarajaya, A., & Maliawan, S. (2006). Kanker kulit. Buletin Alara, 7, 4. Retrieved from http://jurnal.batan.go.id/index.php/Alara/article/view/1577/1495
Irawati, W. (2020). Buku ajar biologi manusia. Tangerang: UPH.
Istighfaricha, S. H. (n.d.). Melanoma, Jenis Kanker Kulit Mematikan Mirip Tahi Lalat. Retrieved from Universitas Airlangga Fakultas Kedokteran: https://fk.unair.ac.id/melanoma-jenis-kanker-kulit-mematikan-mirip-tahi-lalat/
Liokova, K. V., Oberemok, V. V., Krasnodubets, A. M., Gal'chinsky, N. V., Useinov, R. Z., Novikov, I. A., & Volkov, M. E. (2019). Advances in the understanding of skin cancer: ultraviolet radiation, mutation, and antisense oligonucleotides as anticancer drugs. MDPI: Molecules, 1516-1543.
Mardiati, & Maulina, F. (2019). McCune-Albright Syndrome (MAS). Jurnal Averrous, 5(2), 113-126.
Massi, G., & LeBoit, P. (2004). Histological diagnosis of nevi and melanoma. USA: Springer.
Muhartono, & Handriko, R. (2017). Sosialisasi bahaya kanker kulit (melanoma maligna) dan pemeriksaan kesehatan gratis bagi masyarakat di Kecamatan Kamiling Bandar Lampung. JPM Ruwa Jurai, 3, 81-84.
Mulyani, N. S., & Nuryani. (2013). Kanker payudara dan PMS pada kehamilan. Yogyakarta: Nuha Medika.
Naves, L., Dhand, C., Venugopal, J. R., Rajamani, L., Ramakrishna, S., & Almeida, L. (2017). Nanotechnology for the treatment of melanoma skin cancer. Prog Biomater(6), 13-26.
Nickoloff, B., Clark, I., & Hood, L. (2001). Melanoma techniques and protocols: Molecular, diagnosis, treatment, and monitoring. New Jersey: Humana Press.
Nurhayati, S., & Lusiyanti, Y. (2006). Apoptosis dan respon biologik sel sebagai faktor prognosa radioterapi kanker. Iptek Ilmiah Populer, VII, 57-66. Retrieved from http://jurnal.batan.go.id/index.php/Alara/article/view/1577/1495
Prastiwi, T. F. (2012). Kualitas hidup penderita kanker. Development and Clinical Phychology, I, 22. Retrieved from http://journal.unnes.ac.id/sju/index.php/dcp
Pratama, G., Wangko, S., & Jacobs, J. (2010). Peran reseptor melanokortin 1 pada melanogenesis. Jurnal Biomedik, 2(2), 67-77.
Ramda, A. (2014). The miracle of jilbab: Hikmah cantik dan sehat secara ilmiah dibalik syariat jilbab. Yogyakarta: Shahara Digital Publishing.
Risnawati. (2019). Buku ajar: keperawatan intergumen. Klaten: Penerbit Lakeish.
Rosidah, S., Sardjono, Y., & Sumardi, Y. (2017). Analisis dosis BNCT pada kanker kulit melanoma menggunakan MCNPX dengan sumber neutron dari kolom termal reaktor kartini. Jurnal Fisika, 6(5), 352-359.
Sell, S. 2010. On the stem cell origin of cancer. The American Journal of Pathology, 176(6), 2584-2594.
Septian, W., Riana, D., & Prayogo, M. J. (2016). Deteksi diameter tumor pada kulit menggunakan segmentasi citra berdasarkan karakteristik abcde. Informatika, III, 314-232. Retrieved from https://ejournal.bsi.ac.id/ejurnal/index.php/ji/article/view/1311/1073
Setyawan, A., & Djakaria, H. M. (2013). Efek dasar radiasi pada jaringan. Radioterapi dan Onkologi Indonesia, 25-33.
Shead, D., Hanisch, L., & Clarke, R. (2018). NCCN guidelines for patients – melanoma. Fort Washington: NCCN.
Soekin, S., Hermani, B., Adham, M., Hardjoprawito, T. J., Agustian, R. A., & Aroeman, N. A. (2017). Chemotherapy workshop. Oncology head and neck surgery (pp. 23- 53). Bandung: FK UNPAD.
Sudiono, J. (2016). Pemeriksaan patologi untuk diagnosis neoplasma mulut. Makassar: Penerbit Buku Kedokteran.
Tan, S. T., & Dewi, P. I. (2015). Melanoma maligna. Continuing Medical Education, 42, 908-912.
Uripi, V. (2002). Menu untuk penderita kanker. Jakarta: Perpustakaan Nasional RI. Wibowo, D. S. (2015). Anatomi tubuh manusia. Yogyakarta: Graha Imu.
Wilvestra, S., Lestari, S., & Asri, E. (2018). Studi retrospektif kanker kulit di poliklinik ilmu kesehatan kulit dan kelamin RS Dr. M. Djamil padang periode tahun 2015- 2017. Jurnal Kesehatan Andalas, 7.
Authors
This work is licensed under a Creative Commons Attribution 4.0 International License.