Role of Transcription Factors in Banana Fruit Ripening: A Systematic Literature Review
Abstract
Background: The development of edible fruit quality is a vital process. Banana fruit ripening is a complex biochemical and physiological process that causes physical changes such as softening. Fruit aging and ripening are greatly influenced by transcriptional regulation. Transcription factors also play an essential role in regulating various biological processes. Therefore, this study aimed to explore information about the role of transcription factors in banana fruit ripening. Methods: A systematic review was conducted by searching the Scopus database indexed Q1-Q4 through the Watase UAKE application from 2018 to 2023 to find relevant studies on the role of transcription factors in banana fruit ripening. Results: From the search results, 157 articles were found, which were then narrowed down to 11 articles by considering the established inclusion criteria. This study identified 11 transcription factors that have the potential for fruit ripening. Conclusions: The findings of this article review indicate that there are transcription factors, namely MYB, MaWRKY49, MabHLH7, MaNAC42, MaMADS36, bZIP21, MaMYB3, MabHLH, MaERF012, NAC, and WRKY. The role of transcription factors can control fruit quality in agricultural commodities that play genetics in molecular biology. These findings indicate that knowledge of the role of transcription factors can provide insight into the development of innovations in agriculture in the future.
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References
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Chen, H., Lai, X., Wang, L., Li, X., Chen, W., Zhu, X., & Song, Z. (2022). Ethylene Response Factor MaERF012 Modulates Fruit Ripening by Regulating Chlorophyll Degradation and Softening in Banana. Foods, 11(23), 3882.
Chen, T., Qin, G., & Tian, S. (2020). Regulatory network of fruit ripening: current understandings and future challenges. The New Phytologist. https://doi.org/10.1111/nph.16822
Elfman, J., & Li, H. (2020). Detection and measurement of chimeric RNAs by RT-PCR. Chimeric RNA: Methods and Protocols, 83–94.
Fan, Z. Q., Ba, L. J., Shan, W., Xiao, Y. Y., Lu, W. J., Kuang, J. F., & Chen, J. Y. (2018). A banana R2R3‐MYB transcription factor MaMYB3 is involved in fruit ripening through modulation of starch degradation by repressing starch degradation‐related genes and MabHLH6. The Plant Journal, 96(6), 1191–1205.
Jia, C., Wang, Z., Wang, J., Miao, H., Zhang, J., Xu, B., ... & Liu, J. (2022). Genome-wide analysis of the banana WRKY transcription factor gene family closely related to fruit ripening and stress. Plants, 11(5), 662.
Li, B., Fan, R., Yang, Q., Hu, C., Sheng, O., Deng, G., ... & Yi, G. (2020). Genome-wide identification and characterization of the NAC transcription factor family in Musa acuminata and expression analysis during fruit ripening. International Journal of Molecular Sciences, 21(2), 634.
Li, C. (2019). Gene Expression Regulation in Salvia miltiorrhiza. The Salvia Miltiorrhiza Genome, 97–112.
Liu, F., Dou, T., Hu, C., Zhong, Q., Sheng, O., Yang, Q., ... & Bi, F. (2023). WRKY transcription factor MaWRKY49 positively regulates pectate lyase genes during fruit ripening of Musa acuminata. Plant Physiology and Biochemistry, 194, 643–650.
Liu, J., Liu, M., Wang, J., Zhang, J., Miao, H., Wang, Z., ... & Jin, Z. (2021). Transcription factor MaMADS36 plays a central role in regulating banana fruit ripening. Journal of Experimental Botany, 72(20), 7078–7091.
Luchini, C., Veronese, N., Nottegar, A., Shin, J., Gentile, G., Granziol, U., Soysal, P., Alexinschi, O., Smith, L., & Solmi, M. (2020). Assessing the quality of studies in meta‐research: Review/guidelines on the most important quality assessment tools. Pharmaceutical Statistics, 20, 185–195. https://doi.org/10.1002/pst.2068
Mattos, C., & Ruellas, A. (2015). Systematic review and meta-analysis: What are the implications in the clinical practice? Dental Press Journal of Orthodontics, 20, 17–19. https://doi.org/10.1590/2176-9451.20.1.017-019.ebo
Mubarok, S., Al Adawiyah, A. R., Rosmala, A., Rufaidah, F., Nuraini, A., & Suminar, E. (2020). Hormon etilen dan auksin serta kaitannya dalam pembentukan tomat tahan simpan dan tanpa biji. Kultivasi, 19(3), 1217–1222.
Nundy, S., Kakar, A., & Bhutta, Z. (2021). How to Practice Academic Medicine and Publish from Developing Countries? Springer. https://doi.org/10.1007/978-981-16-5248-6_29
Ringer, T., Damerow, L., & Blanke, M. M. (2018). Non-invasive determination of surface features of banana during ripening. Journal of Food Science and Technology, 55, 4197–4203.
Sánchez-Gómez, C., Posé, D., & Martín-Pizarro, C. (2022). Insights into transcription factors controlling strawberry fruit development and ripening. Frontiers in Plant Science, 13, 1022369. https://doi.org/10.3389/fpls.2022.1022369
Skelly M.J, Frungillo L, S. S. H. (2016). Transcriptional regulation by complex interplay between post-translational modifications. Current Opinion in Plant Biology, 33, 126–132.
Song, C. B., Shan, W., Kuang, J. F., Chen, J. Y., & Lu, W. J. (2020). The essential helix-loop-helix transcription factor MabHLH7 positively regulates cell wall-modifying-related genes during banana fruit ripening. Postharvest Biology and Technology, 161, 111068.
Tian, F., Yang, D.C., Meng, Y.Q., Jin, J., Gao, G. (2020). PlantRegMap: charting functional regulatory maps in plants. Nucleic Acids Research, 48(D1), D1104–D1113. https://doi.org/10.1093/nar/gkz1020
Wang, Z., Jia, C., Wang, J. Y., Miao, H. X., Liu, J. H., Chen, C., ... & Jin, Z. (2020). Genome-wide analysis of essential helix-loop-helix transcription factors to elucidate candidate genes related to fruit ripening and stress in Banana (Musa acuminata L. AAA Group, cv. Cavendish). Frontiers in Plant Science, 11, 650.
Wu, C. J., Shan, W., Liu, X. C., Zhu, L. S., Wei, W., Yang, Y. Y., ... & Kuang, J. F. (2022). Phosphorylation of transcription factor bZIP21 by MAP kinase MPK6-3 enhances banana fruit ripening. Plant Physiology, 188(3), 1665–1685.
Wu, J., Fu, L., & Yi, H. (2016). Genome-Wide Identification of the Transcription Factors Involved in Citrus Fruit Ripening from the Transcriptomes of a Late-Ripening Sweet Orange Mutant and Its Wild Type. PLoS One, 11(4), 1–22. https://doi.org/10.1371/journal.pone.0154330
Xiao, Y. Y., Chen, J. Y., Kuang, J. F., Shan, W., Xie, H., Jiang, Y. M., & Lu, W. J. (2013). Banana ethylene response factors are involved in fruit ripening through their interactions with ethylene biosynthesis genes. Journal of Experimental Botany, 64(8), 2499–2510.
Xiao, Y. Y., Kuang, J. F., Qi, X. N., Ye, Y. J., Wu, Z. X., Chen, J. Y., & Lu, W. J. (2018). A comprehensive investigation of the starch degradation process and identification of a transcriptional activator Mab HLH 6 during banana fruit ripening. Plant Biotechnology Journal, 16(1), 151–164.
Yan, H., Jiang, G., Wu, F., Li, Z., Xiao, L., Jiang, Y., & Duan, X. (2021). Sulfoxidation regulation of transcription factor NAC42 influences its functions in relation to stress-induced fruit ripening in banana. Journal of Experimental Botany, 72(2), 682–699.
Yan, H., Wu, F., Jiang, G., Xiao, L., Li, Z., Duan, X., & Jiang, Y. (2019). Genome-wide identification, characterization and expression analysis of NF-Y gene family in relation to fruit ripening in banana. Postharvest Biology and Technology, 151, 98–110.
Yang, Y., Jiang, M., Feng, J., Wu, C., Shan, W., Kuang, J., Chen, J., Hu, Z., & Lu, W. (2021). Transcriptome analysis of low-temperature-affected ripening revealed MYB transcription factors-mediated regulatory network in banana fruit. Food Research International, 148(7), 110616. https://doi.org/10.1016/j.foodres.2021.110616
Yokphonchanachai, C., Songserm, N., Thongprung, S., Thongchai, C., Paengprakhon, Y., Duangsri, J., & Sriwarom, O. (2023). Capacity Building of a Self-Reliant Model Community for Cholangiocarcinoma Prevention by Producing Fruit and Vegetable Juice Products in a High-Risk Area of Thailand. Asian Pacific Journal of Cancer Prevention: APJCP, 24(2), 725–731. https://doi.org/10.31557/APJCP.2023.24.2.725
Zang, N., Li, X., Qi, L., Zhang, Z., Yang, Y., Yin, Z., & Wang, A. (2023). H2O2-activated transcription factor MdERF4 negatively regulates ethylene biosynthetics during fruit ripening by suppressing MdACS1 transcription. Postharvest Biology and Technology, 204, 112461.
Zaret, K. S. (2020). Pioneer transcription factors initiate gene network changes. Annual Review of Genetics, 54, 367–385. https://doi.org/10.1146/annurev-genet-030220-015007
Authors
Ayuwaningsih, M. S., Setiati, N., & Anggraito, Y. U. (2025). Role of Transcription Factors in Banana Fruit Ripening: A Systematic Literature Review. BIOEDUSCIENCE, 9(1), 1–10. https://doi.org/10.22236/jbes/13694
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