Article Sidebar

Submitted
13 August 2022
Accepted
14 August 2022
Published
31 August 2022
Download
PDF
Statistic
Read Counter : 278 Download : 290

Downloads

Download data is not yet available.

Main Article Content

Abstract

Background: Tuberkulosis paru merupakan penyakit menular langsung yang disebabkan oleh kuman Mycobacterium tuberculosis. Salah satu upaya pengobatannya dengan kombinasi suplemen herbal madu kelulut berasal dari lebah Trigona spp yang dimanfaatkan dalam penyembuhan berbagai penyakit. Untuk mengetahui pengaruh suplemen madu kelulut terhadap peengurangan efek samping penggunaan obat anti tuberkulosis paru (OAT). Metode: Literature review sebanyak 7 yang diperoleh dari Google Scholar, Garuda Riste dikti, dan Malaysian Journal of Science (MJS). Hasil: Suplemen madu kelulut berpengaruh terhadap daya tahan tubuh (5,43%), peningkatan neutrofil (13,04%), mampu menekan resistensi obat (54,71%), sebagi pelengkap Neutraceutical calon obat anti tuberkulosis (5,07%), menstabilkan kadar lukosa darah (21,73%). Kesimpulan: Suplemen madu kelulut menjadi pelengkap nutraceutical yang diharapkan dapat mengurangi efek samping Obat Anti Tuberkulosis (OAT), efek samping mengkonsumsi OAT akan selalu menimbulkan gangguan pencernaan, perkemihan, dan gangguan persyarafan.

Keywords

Effect Kelulut Honey Medicine Efek Madu Kelulut Obat

Article Details

License
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

© 2022 Oleh authors. Lisensi Jurnal Solma, LPPM-Uhamka, Jakarta. Artikel ini bersifat open access yang didistribusikan di bawah syarat dan ketentuan Creative Commons Attribution (CC BY) license. (http://creativecommons.org/licenses/by/4.0/).

How to Cite
Ardenny Ardenny. (2022). Literature review: Pengaruh Suplemen Madu Kelulut terhadap Pengurangan Efek Samping Penggunaan Obat Anti Tuberkulosis Paru (OAT). Jurnal SOLMA, 11(2), 381–392. https://doi.org/10.22236/solma.v11i2.9592
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. Al-Dabbas, M. M., Otoom, H. A., & Al-Antary, T. M. (2019). Impact of honey color from Jordanian flora on total phenolic and flavonoid contents and antioxidant activity. Fresenius Environmental Bulletin, 28(9), 6898–6907.
  2. Al-Farsi, M., Al-Amri, A., Al-Hadhrami, A., & Al- Belushi, S. (2018). Color, flavonoids, phenolics, and antioxidants of Omani. Heliyon, 4(10), 1–14. https://doi.org/10.1016/ j.heliyon.2018.e00874.
  3. Arimbi, & Rahman, A. (2017). Efek Tonik Madu dan Telur terhadap Daya Tahan. Proceeding of Ntional Seminar.
  4. Avila, S., Beux, M. R., Ribani, R. H., & Zambiazi, R. C. (2018). Stingless bee honey: Quality parameters, bioactive compounds, health-promotion properties, and modification detection strategies. Trends in Food Science & Technology, 81, 37–50. https://doi.org/10.1016/j.tifs.2018.09.002
  5. Bogdanov, S. (2010). Honey as Nutrient and Functional Food. In Book of Honey, Chapter 7 (pp. 1–28).
  6. Boorn, K. L., Khor, Y. Y., Sweetman, E., Tan, F., & Heard, T. A. (2019). Antimicrobial activity of honey from the stingless bee Trigona carbonaria determined by agar diffusion, agar dilution, broth microdilution, and time-kill methodology. Journal of Applied Microbiology, 108(5), 1534–1543. https://doi.org/10.1111/j.1365-2672.2009.04552.x
  7. da Silva, I. A. A., da Silva, T. M. S., Camara, C. A., Queiroz, N., Magnani, M., de Novais, J. S., & de Souza, A. G. (2013). Phenolic profile, antioxidant activity and palynological analysis of stingless bee honey from Amazonas, Northern Brazil. Food Chemistry, 141(4), 3552–3558. https://doi.org/10.1016/j.foodchem.2013.06.072
  8. Dahliansyah, D., & Petrika, Y. (2020). Pemberian Madu Trigona Sp. (Kelulut) Dan Sari Jeruk Siam Sambas Terhadap Kadar Hemoglobin Darah (Hb) Ibu Hamil. Jurnal Surya Medika, 6(1). https://doi.org/10.33084/jsm.v6i1.1630
  9. Dwiyanti, R. D., Nurlailah, N., & Widiningsih, I. K. (2015). Efektivitas Air Rebusan Daun Binahong (Anredera cordifolia) terhadap Pertumbuhan Salmonella typhi. Medical Laboratory Technology, 1, 1–6.
  10. Erawatyningsih, P., & Heru, S. E. (2012). Faktor-Faktor yang Mempengaruhi Ketidakpatuhan Berobat pada Penderita Tuberkulosis Paru. Jurnal Berita Kedokteran Masyarakat (BKM), 25(3), 117–124.
  11. Febriyanti, A., Jiu, C. K., & Ariyanti, S. (2020). Efektivitas Jenis-Jenis Madu (Madu Hutan, Madu Kelulut Dan Madu Ternak) Terhadap Kadar Gula Darah. Jurnal Keperawatan Dan Kesehatan, 11(1), 12–20. https://doi.org/10.54630/jk2.v11i1.114
  12. Fikri, N., Taurina, W., & Andrie, M. (2019). Formulasi Sediaan Salep Madu Kelulut (Heterotrigona itama) dan Adeps Lanae terhadap Stabilitas Sifat Fisik Sediaan Selama Masa Penyimpanan. In Jurnal Farmasi Kalbar.
  13. George, S., & Benny, P. (2010). A Review on the Medicinal Significance of Common Fruits. International Journal Of Biomedical Research And Analysis, 1(2), 60–64.
  14. Hamad, S. (2017). Terapi Madu: Panduan Praktis untuk 84 Penyakit, Plus untuk Stamina Mental. Pustaka Ilman.
  15. Haryanto, B., Hasan, Z., Kuswandi, & Artika. (2016). Penggunaan Propolis untuk Meningkatkan Produktivitas Ternak Sapi Peranakan Ongole (PO). Indonesian Journal of Animal and Veterinary Science, 17(3), 202.
  16. Hermayanti, D. (2010). Studi Kasus Drop Out Pengobatan Tuberkulosa (TB) di Puskesmas Kodya Malang. Staff Pengajar Fakultas Kedokteram Universitas Muhammadiyah Malang, 43–50.
  17. Hijriah, R., & Winarsih, S. (2014). Efek Antibakteri Madu Apel dan Madu Klanceng terhadap Staphylococcus aureus Isolat 034p secar a In Vitro, . Fak. Kedokt. Univ. Brawijaya Malang. Jurnal Penelitian Fakultas Kedokteran.
  18. Kemenkes RI. (2018). Pertemuan Nasional Evaluasi dan Perencanaan Program Pengendalian Tb Tahun 2018. Kemenkes RI.
  19. Kumar, A., & Sharma, S. (2008). An Evaluation of Multipurpose Oil Seed Crop for Industrial Uses (Jathropa curcas L.): A Review. Industrial Crops and Products, 28(1), 1–10. https://doi.org/10.1016/j.indcrop.2008.01.001
  20. Kurniati, I. (2010). Angka Konversi Penderita Tuberkulosis Paru yang Diobati dengan Obat Anti Tuberkulosis (OAT). Paket Kategori Satu Di BP4 Garut, 42(1).
  21. Ma’ruf, M., Mawaddah, G. A., Eriana, N. N. A., Swari, F. I., Aslamiyah, S., & Lutpiatina, L. (2018). Madu lebah kelulut (Trigona Spp.) dalam aktifitas terhadap bakteri Staphylococcus aureus resisten. Jurnal Skala Kesehatan, 9(1), 1–6. https://doi.org/10.31964/jsk.v9i1.151
  22. Mahani, Sulaeman, A., M., A. R., Damanik, Hardinsyah, & Ploege, R. (2018). Determination of Indonesian native stingless bee propolis as complementary nutraceutical candidate of anti-tuberculosis drug. International Journal of Pharmacy and Pharmaceutical Science, 4(10). https://doi.org/10.22159/ijpps.2018v10i4.23850
  23. Nweze, J. A., Okafor, J. I., Nweze, E. I., & Nweze, J. E. (2017). Evaluation of physicochemical and antioxidant properties of two stingless bee kinds of honey: A comparison with Apis mellifera honey from Nsukka, Nigeria. BMC Research Notes, 10(1), 1–6. https://doi.org/10.1186/ s13104-017-2884-2
  24. Rahmah, S., Herda, A., & Dedi, H. (2021). Studi Literatur Efek Samping Obat pada Pasien tuberkulosis. Journal of Current Pharmaceutical Sciences, 4(2), 395–405.
  25. Rahmayuni, Faizah, H., & Fifin, N. (2013). Penambahan Madu dan Lama Fermentasi Susu Fermentasi Kacang Merah. SAGU, 12(1), 25–33.
  26. Rao, P. V., Krishhnan, K. T., Salleh, N., & Gan, S. H. (2016). Biological and therapeutic effects of honey produced by honey bees and stingless bees: a comparative review. Revista Brasileira de Farmacognosia, 26(5), 657–664. https://doi.org/10.1016/j. bjp.2016.01.012
  27. Rashid, M. R., Aripin, K. N. N., Mohideen, F. B. S., Baharom, N., Omar, K., Taujuddin, N. M. S. M., Yusof, H. H. M., & Addnan, F. H. (2019). The Effect of Kelulut Honey on Fasting Blood Glucose and Metabolic Parameters in Patients with Impaired Fasting Glucose. Journal of Nutrition and Metabolism. https://doi.org/10.1155/2019/3176018
  28. Rian, S. (2010). Pengaruh Efek Samping Obat Anti Tuberkulosis Terhadap Kejadian Default di Rumah Sakit Islam Pondok Kopi Jakarta Timur Januari 2008–Mei 2010. Tesis.
  29. Ridoni, R., Radam, R., & Fatriani. (2020). Analisis Kualitas Madu Kelulut (Trigona sp) dari Desa Mangkauk Kecamatan Pengaron Kabupaten Banjar. Jurnal Sylva Scienteae, 3(2), 346–355.
  30. Roy, S., & Mandal, S. (2019). View of color intensity and antioxidative capacity of four natural monofloral honey from Malda, India. Asian Journal of Pharmaceutical and Clinical Research, 12(9), 111–115. https://doi.org/10.22159/ajpcr.2019.v12i9.34352
  31. Saludin, S. F., Kamarulzaman, N. H., & Ismail, M. M. (2019). Measuring consumers’ preferences of stingless bee honey (meliponine honey) based on sensory characteristics. International Food Research Journal, 26(1), 225–235.
  32. Samarghandian, S., Farkhondeh, T., & Samini, F. (2017). Honey and Health: A Review of Recent Clinical Research. Pharmacognosy Res, 9(2), 121–127. https://doi.org/10.4103/0974-8490.204647
  33. Sari, I. D., Yuniar, Y., & Yaripuddin, M. (2014). Studi Monitoring Efek Samping Obat Anti Tuberkulosis FDC Kategori 1 di Provinsi Banten dan Provinsi Jawa Barat. Media Litbangkes, 24(1), 28–35.
  34. Sharma, M., Khayyam, K. U., Kumar, V., & Imam, F. (2008). Influence of honey on adverse reactions due to anti-tuberculosis drugs in pulmonary tuberculosis patients. Continental J. Pharmacology and Toxicology Research, 2, 6–11.
  35. Sinha, K., Marak, I. R., & Singh, W. A. (2013). Adverse drug reactions in tuberculosis patients due to directly observed treatment strategy therapy: Experience at an outpatient clinic of a teaching hospital in the city of Imphal Manipur, India. The Journal of Association of Chest Physicians, 1(2), 50–53.
  36. Sivakumar, A., & Jayaraman, G. (2011). Anti-tuberculosis activity of commonly used medicinal plants of south India. Journal of Medicinal Plants Research, 5(31), 6881–6884. https://doi.org/10.5897/JMPR11.1397
  37. Sulieman, A. M. E., Abdelhmeid, B. A., & Salih, Z. A. (2013). Quality evaluation of honey obtained from different resources. Food and Public Health, 3(3), 137–141. https://doi.org/10.5923/j.fph.20130303.04
  38. Suranto, A. (2014). Khasiat dan Manfaat Madu Herbal. PT Agro Media Pustaka.
  39. Tamara, A., Oktiani, B. W., & Taufiqurrahman, I. (2019). Pengaruh ekstrak flavonoid propolis kelulut (G.thoracica) terhadap jumlah sel netrofil pada periodontitis (Studi In Vivo Pada Tikus Wistar (Rattus norvegicus) Jantan). Dentin: Jurnal Kedokteran Gigi, 3(1).
  40. WHO. (2013). Operational Guide for National Tuberculosis programs. WHO Report.
  41. Ya, H., Fatiha Norhisham, N., Mohamed, M., Sadek, N., & Endrini, S. (2019). Evaluation of Physicochemical Properties of Trigona sp. Stingless Bee Honey from Various Districts of Johor (Kajian fizikokimia terhadap Trigon sp. Madu Lebah Kelulut di Daerah Johor). Jurnal Kejuruteraan SI, 2(1), 59–67. https://doi.org/10.17576/jkukm-2019-si2(1)-08
  42. Yumantoko, Y., & Ramdiawan, R. (2021). The Competitiveness of Honey Kelulut Lombok, West Nusa Tenggara Province. Jurnal Penelitian Kehutanan Faloak, 5(2), 118–131. https://doi.org/10.20886/jpkf.2021.5.2.118-131